Article: Connectomic and Surface-Based Morphometric Correlates of Acute Mild Traumatic Brain Injury.
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Dall'Acqua P; Johannes S; Mica L; Simmen HP; Glaab R; Fandino J; Schwendinger M; Meier C; Ulbrich EJ; Müller A; Jäncke L; Hänggi J
Front Hum Neurosci, 2016
Table 1
Characteristics of patient and control groups .
Patients ( n 51) Controls ( n 53) p -value (two-sided)
Gender (female/male) 19/32 20/33 0.960
Handedness (right/left) 46/5 44/9 0.284
Mean SD Range (Min./Max.) Mean SD Range (Min./Max.)
Age (years)
34.5
12.4
18/61
34.2
12.1
18/60
0.887
Education (years)
12.5
2.5
8/18
12.8
2.4
7/19
0.509
GCSa
14.8
0.4
13/15
–
–
–
–
Number of mTBI in the past
0.6
0.9
0/4
0.4
0.8
0/3
0.271
SURFACE-BASED MEASURES
Total surface area (cm2 )
171.74
17.31
130.68/210.99
173.53
13.32
147.80/211.03
0.555
Mean cortical thickness (mm2 )
2.47
0.11
2.21/2.79
2.45
0.11
2.19/2.66
0.300
Total gray matter volume (cm3 )
639.89
65.32
479.70/767.50
639.93
53.58
533.99/735.49
0.998
Total white matter volume (cm3 )
483.51
59.40
364.66/592.62
487.01
38.37
398.69/557.22
0.723
Total subcortical gray matter volume (cm3 )
61.58
5.33
48.50/75.89
61.20
4.12
53.62/72.60
0.687
CONNECTIVITY MEASURES (90 NODES)
Total number of streamlines
2,156,105
244,298
1,501,810/2,661,329
2,145,401
171,886
1,751,206/2,519,561
0.797
Streamlines omitted
1,372,326
135,137
1,106,589/1,628,276
1,355,014
117,186
1,130,381/1,573,362
0.486
Streamlines used to populate matrix
832,291
145,735
445,646/1,142,486
836,944
95,077
609,833/1,110,992
0.848
Selfloops
466,828
70,021
290,453/613,120
463,774
43,599
386,019/574,392
0.791
NEUROPSYCHOLOGICAL ASSESSMENT
RPQ (total score)b
13.98
10.80
0/46
2.85
4.15
0/20
<0.001c
Go/Nogo (ms)
398.71
67.92
246/558
370.38
44.54
286/497
0.007c
Divided attention, visual (ms)
803.12
104
628/1075
754
87.34
605/985
0.005c
a
GCS, Glasgow coma scale;
b
RPQ, Rivermead Post-Concussion Symptoms Questionnaire;
c
one-sided differences between groups after adjustment for multiple testing. The Bonferroni-corrected significance level was set at p < 0.0047 taking into account the mean correlation (r = 0.21) of the 20 variables tested. All other neuropsychological scores are illustrated in Supplementary Table 1 .
Inferred neuron-electrophysiology data values
Neuron Type
Neuron Description
Ephys Prop
Extracted Value
Standardized Value
Content Source
